Hematopoietic Stem Cell Transplantation

   Remarkable developments in the field of transplantation have created opportunities to address the formidable challenges of transplantation across histocompatibility barriers, stem cell expansion, and prevention of complications and generation of graft-vs-tumor activity to eradicate residual disease. Stem Cell Transplantation for Hematologic and Other Disorders, Second Edition provides a glimpse into potential future applications of bone marrow derived stem cells in the field of cardiac repair. The updated chapters introduce the biologic underpinnings of hematopoietic cell transplantation, basic stem cell biology, immunobiology, and histocompatibility, with emphasis on indications and results of transplantation for specific diseases. Written by experts in the field, Stem Cell Transplantation for Hematologic Disorders, Second Edition provides seasoned professionals with a complete understanding of the current state of transplantation biology as well as a clear vision into the future.

• New edition with updated current state of the science

• Nine new chapters added

• Comprehensive understanding of the current state of transplantation biology

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Front Matter
    Pages i-xvi
    PDF
    Biology of Transplantation
        Stem Cell Biology
            Elizabeth O. Hexner, Stephen G. Emerson
        Pages 3-18
        Stem Cell Transplantation for Hematologic Malignancies
            Effie W. Petersdorf
        Pages 19-38
        Immunobiology of Transplantation
            Robert S. Negrin
        Pages 39-54
    Transplantation for Specific Disorders
        Allogeneic and Autologous Hematopoietic Stem Cell Transplantation for Acute Lymphoblastic Leukemia and Acute Myelogenous Leukemia in the Adult
            Stein and Anthony, Forman J. Stephen
        Pages 57-82
        Hematopoietic Cell Transplantation for Chronic Myeloid Leukemia
            Uday Popat, Sergio Giralt
        Pages 83-104
        Stem Cell Transplantation for Hodgkin's and Non-Hodgkin's Lymphomas
            John W. Sweetenham
        Pages 105-136
        Transplantation in Chronic Lymphocytic Leukemia
            Rifca Le Dieu, John G. Gribben
        Pages 137-147
        Stem Cell Transplantation in Multiple
            John Koreth, Kenneth C. Anderson
        Pages 149-166
        Allogeneic Hematopoietic Cell Transplantation for Patients with Myelodysplastic Syndrome and Myeloproliferative Disorders
            Aravind Ramakrishnan, H. Joachim Deeg
        Pages 167-182
        Stem Cell Transplantation for Marrow Failure
            Philippe Armand, Joseph H. Antin
        Pages 183-200
        Stem Cell Transplantation for Hemoglobinopathies
            Catherine J. Wu MD
        Pages 201-221
    Alternative Stem Cell Sources
        Stem Cell Sources for Allogeneic Transplantation
            Corey Cutler
        Pages 225-244
        Allogeneic Unrelated Donor Blood and Marrow Transplantation
            Daniel Daniel Weisdorf
        Pages 245-265
        Umbilical Cord Hematopoietic Stem Cell Transplantation
            Mitchell E. Horwitz, Nelson Chao
        Pages 267-288
        Haploidentical Stem Cell Transplantation
            R. Dey Bimalangshu, Thomas R. Spitzer
        Pages 289-317
    Conditioning Regimens
        Ablative Preparative Regimens for Hematopoietic Stem Cell Transplantation
            Amin Alousi, Marcos de Lima
        Pages 321-347
        Nonmyeloablative Transplantation
            Frédéric Baron, Brenda M. Sandmaier
        Pages 349-374
    Complications of Transplantation
        Immune Reconstitution after Allogeneic Transplantation
            Carolyn A. Keever-Taylor
        Pages 377-420
        Infection in the Hematopoietic Stem Cell Transplant Recipient
            Francisco M. Marty, Lindsey R. Baden
        Pages 421-448